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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1615 | Irbesartan | SR-47436,BMS-186295 | Apoptosis , RAAS |
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist. | |||
T1605L | Enalapril sodium | (-)-Enalapril sodium | |
Enalapril sodium is used to treat high blood pressure, diabetic kidney disease, and heart failure and can be generally used with a diuretic such as furosemide for heart failure. | |||
T73332 | BI-685509 | ||
BI-685509 is a potent and orally active sGC activator. BI-685509 restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. BI-685509 can be used in research of chronic kidne... | |||
T74097 | THX-B | ||
THX-B, a potent non-peptidic antagonist of the neurotrophin receptor p75 (p75 NTR), is utilized in the study of diabetic kidney disease, neurodegenerative, and inflammatory disorders [1] [2] [3]. | |||
T77988 | Phenyl sulfate | Phenyl hydrogen sulfate | Endogenous Metabolite |
Phenyl sulfate, an orally active metabolite derived from gut microbiota, induces albuminuria and podocyte damage in diabetes experimental models. It serves as a potential disease marker and therapeutic target for diabeti... | |||
T73760 | Epsilon-(gamma-glutamyl)-lysine TFA | ||
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA, an N(6)-acyl-L-lysine derivative, plays a crucial role in the formation of epsilon-(gamma-glutamyl)lysine crosslinks within the extracellular matrix (ECM) compone... |